Synthesis of a disaccharide of phenolic glycolipid from Mycobacterium leprae (PGL-I) and its conjugates with bovine serum albumin
| Autor: | Vladimir I. Torgov, T. V. Chekryzhova, T. M. Mel´nikova, Alexander O. Chizhov, Leonid O. Kononov, M. V. Mel´nikova, N. N. Kondakov, Alexander I. Zinin |
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| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
biology 010405 organic chemistry Stereochemistry Glycoconjugate Disaccharide Glycoside General Chemistry 010402 general chemistry biology.organism_classification 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Glycolipid chemistry Biochemistry biology.protein Bovine serum albumin Mycobacterium leprae Conjugate |
| Zdroj: | Russian Chemical Bulletin. 64:1142-1148 |
| ISSN: | 1573-9171 1066-5285 |
| DOI: | 10.1007/s11172-015-0991-6 |
| Popis: | Terminal disaccharide fragment of phenolic glycolipid from Mycobacterium leprae (PGL-I) was synthesized as a glycoside with 4-(2-aminoethoxy)phenyl aglycon. The obtained 4-(2-aminoethoxy)phenyl 4-O-(3,6-di-O-methyl-β-d-glucopyranosyl)-2,3-di-O-methyl-α-l-rhamnopyranoside was used for the synthesis of a series of neoglycoconjugates with bovine serum albumin with different degrees of substitution. |
| Databáze: | OpenAIRE |
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