Plasma B-type natriuretic peptide levels in children with heart disease
| Autor: | Urs Bauersfeld, Walter Knirsch, Peter Gessler, Margrit Fasnacht, Eliane Häusermann, Martin Hersberger |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Heart disease Medical treatment business.industry medicine.drug_class General Medicine medicine.disease Pulmonary hypertension Tertiary care Clinical trial Internal medicine Heart failure Pediatrics Perinatology and Child Health medicine Natriuretic peptide Cardiology cardiovascular diseases business hormones hormone substitutes and hormone antagonists Paediatric patients |
| Zdroj: | Acta Paediatrica. 100:1213-1216 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.2011.02258.x |
| Popis: | Aim: To determine plasma B-type natriuretic peptide (BNP) levels in children with heart diseases before medical or surgical treatment for monitoring therapeutic efficacy in an observational prospective clinical trial at tertiary care centre. Methods: In 522 paediatric patients at an age of 6.4 ± 5.2 years (mean ± SD; range: 14 days–18 years) with congenital heart disease (CHD), cardiomyopathies (CMP) or pulmonary arterial hypertension (PAH), plasma BNP levels were evaluated before and under treatment. Results: Most types of heart disease are associated with increased mean plasma BNP levels before treatment, with highest values in children with CMP (BNP 6165 pg/mL in dilated CMP vs. 817 pg/mL in hypertrophic, vs. 1236 pg/mL in restrictive CMP, each p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text