Triphenyl phosphate end-capped dicyanomethylene-4H-pyran as a near infrared fluorescent sensor for lysozyme in urine sample

Autor: Yi Qu, Le Wang, Mengsheng Xu, Jipeng Chen, Yunxia Yang
Rok vydání: 2019
Předmět:
Zdroj: Sensors and Actuators B: Chemical. 284:553-561
ISSN: 0925-4005
DOI: 10.1016/j.snb.2019.01.001
Popis: A dicyano-methylene-4H-pyran (DCM)-based fluorescent probe DCPOP was designed for detecting lysozyme in urine sample. DCPOP showed obvious NIR emission (> 650 nm) avoiding the background fluorescence of urine (450 ˜ 600 nm). Compared to its mimic (DCPO), DCPOP has a big end-capped triphenyl phosphate (TPP) moiety, which induced good stability in several aqueous with different pH value. Furthermore, the end-capped TPP moiety showed weak interaction with lysozyme, which could modulate the emission signals of DCPOP. As a result, DCPOP could detect the lysozyme in both PBS buffer and real urine samples.
Databáze: OpenAIRE