A case of hyperammonemia in a patient with urinary tract infection and urinary retention

Autor: Sat Prasad Nepal, Yoshiko Maeda, Yoshio Ogawa, Ryosuke Kato, Michio Naoe, Hiroo Sugishita, Tsutomu Unoki, Kazuhiko Oshinomi, Takehiko Nakasato, Jun Morita, Tatsuki Inoue, Takeshi Shichijo, Madoka Omizu
Rok vydání: 2020
Předmět:
Zdroj: Urological Science. 31:82
ISSN: 1879-5226
DOI: 10.4103/uros.uros_70_19
Popis: Excessive ammonia is harmful to the body. It is mostly hepatic in origin. Hyperammonemia due to urinary tract infection (UTI) is rare. We report a case of hyperammonemia with UTI and urinary retention. A 94-year-old female arrived at our hospital with impaired consciousness that lasted for a day. On arrival, her Glasgow Coma Scale was E1V1M5, blood ammonia was 272 ng/dl, and urinalysis revealed a large number of white and red blood cells. Abdominal computed tomography scan revealed a distended bladder and wall thickness with no hydronephrosis. Urine cultures were positive for urease-producing Corynebacterium, Escherichia coli, and Staphylococcus aureus. The patient was diagnosed with hyperammonemia with UTI and urinary retention. After urinary catheterization, blood ammonia levels normalized, and consciousness improved. We need to consider ammonia toxicity in UTI patients with urine retention presenting with altered consciousness.
Databáze: OpenAIRE
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