Cytokine production by peripheral blood lymphocytes in patients with ovarian epithelial tumors

Autor:	R. V. Pavlov, V. A. Aksenenko, A. Yu. Krivoruchko, N. A. Pavlenko
Rok vydání:	2021
Předmět:	Obstetrics and Gynecology
Zdroj:	Journal of obstetrics and women's diseases. 50:37-40
ISSN:	1683-9366 1684-0461
Popis:	In presence of autoserum, production of IL1b, IL2, IL4, IL6 and TNFa by peripheral blood lymphocytes of 30 patients with epithelial tumors of ovaries and 50 patients with epithelial ovarian cancer of I-IV stages was investigated. The data received enable to ascertain the increase of mononuclear activity during ovarian tumor progression, increase of T-helpers of the second type activity, along with the reduction of T-helpers of the first type activity in peripheral blood of patients, and abnormalities of IL6-dependent mechanism of control of ILIb and TNFa production by peripheral blood lymphocytes of patients with ovarian cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8453745690c2f86a9d91730f4e12733 https://doi.org/10.17816/jowd89004 Zobrazit plný text záznamu