Autor:	Joseph B. Sweeney, Smita Thobhani, Alan F. Haughan, J. R. Knight
Rok vydání:	2007
Předmět:	chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Regioselectivity Biochemistry Derivative (chemistry)
Zdroj:	Tetrahedron. 63:2729-2737
ISSN:	0040-4020
Popis:	In contrast to the corresponding hydroxyiodination reactions, the reaction of acetoxycyclohex-2-ene 1 with N-PSP in the presence of water shows little regiocontrol, but is highly diastereoselective. However, the same reaction of the (R)-phenylglycinate derivative of (±)-cyclohexen-3-ol is highly diastereoselective, and regioselective. A hydrogen-bonding interaction is proposed to rationalize these differing selectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8209974669d189033a3486ff7586082 https://doi.org/10.1016/j.tet.2006.12.035 Zobrazit plný text záznamu Full Text from ScienceDirect