Iodobenzene-catalyzed oxidative C H d-alkoxylation of quinoxalinones with deuterated alcohols

Autor: Jun Qiao, Wenbo Yu, Chao Shen, Jianzhong Jin, Jianying Tong
Rok vydání: 2020
Předmět:
Zdroj: Catalysis Communications. 141:106008
ISSN: 1566-7367
DOI: 10.1016/j.catcom.2020.106008
Popis: A convenient and practical iodobenzene-catalyzed synthesis of trideuteroalkoxylated quinoxalinones has been developed under transition-metal-free conditions. The present transformation can be accomplished through C H/O H cross-dehydrogenative-coupling of quinoxalinones with deuterated alcohol. Various substrates are compatible, providing the corresponding products in moderate to good yields. A free radical pathway mechanism is advised for the transformation.
Databáze: OpenAIRE