Chemometrics data analysis and controversial carcinogenic effect of Ocimum basilicum L. rich in methyl eugenol

Autor: Nilüfer Vural
Rok vydání: 2021
Předmět:
Zdroj: Journal of Food Measurement and Characterization. 15:4825-4837
ISSN: 2193-4134
2193-4126
DOI: 10.1007/s11694-021-01072-9
Popis: Ocimum basilicum (Lamiaceae) commonly known as Sweet Basil is an aromatic plant having a controversial carcinogenic effect and is also used in the food industry. This study was designed to evaluate the chemical constituent by the chemometrics-assisted-GCMS and the antioxidant activity of the O. basilicum L. herb gathered from Sivas. Twenty-one ingredients representing 92.30% of the total oil were identified in the essential oil of O. basilicum L. The major ingredients were noted as methyl eugenol 52.97%, α-cubebene 10.82%, and spathenole 6.92%. The results were compared with other studies on the content of the O. basilicum L. plant. DPPH and β-carotene-Linoleic acid assays revealed considerable antioxidant activity of methyl eugenol-rich O. basilicum essential oil, which is lower than standard BHT, and higher than standard methyl eugenol. Multivariate curve resolution-alternative least squares (MCR-ALS) which is an iterative method was used for resolving the overlapped and embedded peaks. The results of this study show that chromatographic methods combined with MCR-ALS analysis techniques can be useful for a comprehensive, rapid, and specific analysis of complex natural products such as O. basilicum essential oils. In recent studies, the carcinogenic effects of methyl chavicol and methyl eugenol, the dominant active ingredients of O. basilicum L. were pointed.
Databáze: OpenAIRE
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