| Popis: |
Since December 2019, a novel pneumonia caused by a novel coronavirus (SARS-CoV-2) has spread through the whole world. There are various ways to control the outbreak, such as vaccines, neutralizing antibodies, but prophylactic measures is still one of the important measures to control the outbreak like face masks. Montmorillonite-Nasal-Gel (MNG), a nasal spray gel consisting of a combination of 10% montmorillonite, 2% xylitol and water, has shown the effect to reduce viral infection. We tested the effect of MNG on SARS-CoV-2 infection by using a SARS-CoV-2 S protein pseudovirus system. To evaluate the efficacy of MNG against SARS-CoV-2 infection, SARS-CoV-2 were treated with 50% MNG in BSL-3 laboratory. These experiments appeared that MNG treatment greatly reduced the infection of SARS-CoV-2. As a nasal spray, it should not stimulate the airways. So we did a respiratory stimulating test and found that it has no stimulating effect on the respiratory tract. Montmorillonite is generally considered to have a amount of negative charge on the surface, it can absorb some viruses and bacteria. We assume that montmorillonite can physically adsorb SARS-CoV-2 too. As a personal protective equipment, MNG was approved by National Medical Products Administration (NMPA). MNG can further be used in the protection of all groups. |
