Central Precocious Puberty in a Three-Year-Old Girl
Autor: | R. Satriono, Ratna Dewi Artati, Suryani Jamal, Ruland Dn Pakasi, Suci Aprianti, Liong Boy Kurniawan |
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Rok vydání: | 2021 |
Předmět: |
Gynecology
Breast development medicine.medical_specialty Every Six Months medicine.diagnostic_test Secondary sex characteristic business.industry Physical examination Bone age medicine.disease Leuprorelin General Earth and Planetary Sciences Medicine Precocious puberty Vaginal bleeding medicine.symptom business General Environmental Science medicine.drug |
Zdroj: | INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 27:341-345 |
ISSN: | 2477-4685 0854-4263 |
DOI: | 10.24293/ijcpml.v27i3.1568 |
Popis: | Precocious puberty is defined as the onset of secondary sexual characteristics before 8 years of age in girls and 9 years in boys. Central Precocious Puberty (CPP) is caused by early activation of the hypothalamic-pituitary-gonadal axis. Laboratory test of LH, FSH, and Estradiol is recommended for monitoring suppressive effects from GnRHa therapy in the early three months and every six months. This study aimed to report a case of CPP in a 3-year and 3-month-old girl. A 3-year and 3-month-old girl went to the hospital with vaginal bleeding (menstruation), breast development, and pubic and axilla hair for 7-month-old. Physical examination found moderately ill with obesity, body weight 20 kg, height 98 cm. Tanner stage was A2M3P2, café au lait was found in the left forehead with size 7x3.5 cm. In March 2015 before GnRHa therapy, LH, FSH and Estradiol level increased with levels of 4.32 mlU/mL, 6.01 mlU/mL, and 67 pg/mL, and after 3 months of the treatment was 0.87 mlU/mL, 2.51 mlU/mL and |
Databáze: | OpenAIRE |
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