Use of porous biodegradable polymer implants in meniscus reconstruction. 2) Biological evaluation of porous biodegradable polymer implants in menisci

Autor: A. J. Nijenhuis, H. Elema, J.H. de Groot, René P. H. Veth, H.W.B. Jansen, J. Klompmaker, Aj Pennings
Rok vydání: 1990
Předmět:
Zdroj: Colloid and Polymer Science. 268:1082-1088
ISSN: 1435-1536
0303-402X
DOI: 10.1007/bf01410673
Popis: Several series of porous, biodegradable PU/PLLA foams were used for meniscus reconstruction in dogs. PLLA-fiber reinforced PU/PLLA composites, PU/PLLA, and PU foams were implanted in severe meniscus lesions. The healing process was initiated as a result of blood vessels′ and other cells′ ingrowth into these porous materials. To accomplish good ingrowth of fibrocartilaginous tissue, the materials should have interconnected macropores of 200–300μn with a high total pore volume. PLLA fibers were used to reinforce the materials, but seem to retard the degradation process and the ingrowth of fibrocartilaginous tissue.
Databáze: OpenAIRE