Nanostructured Porous Silicon Containers as Drug Carriers

Autor:	A. G. Akopdzhanov, A. A. Belogorlov, N. L. Shimanovsky, S. A. Bortnikova
Rok vydání:	2021
Předmět:	Pharmacology Biocompatibility 010405 organic chemistry Chemistry Drug release kinetics Design elements and principles Nanotechnology Porous silicon 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry Drug Discovery Drug release Surface modification Porosity Drug carrier
Zdroj:	Pharmaceutical Chemistry Journal. 54:1063-1066
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-021-02320-4
Popis:	The possibilities of using porous silicon nanostructured containers as drug carriers are considered. The main design principles of the nanocontainers and the possibility of using pore surface modification to achieve the optimal regimes of drug loading and controlled in vivo drug release are formulated. Results from studies devoted to the application of porous silica containers are presented. The main prospects and research tasks in this field are related to reducing the object size, increasing the biocompatibility, increasing the drug loading volume, and achieving the optimal drug release kinetics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a7e1ed84c4b638fe69f6994c3f0d37d3 https://doi.org/10.1007/s11094-021-02320-4 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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