Evaluation of the extracts of Xylopia villosa Chipp (Annonaceae) on the lipid profile of rats rendered diabetic by streptozocin

Autor:	Okpekon Aboua Timothée, Kouame Yao Yves, Yapi Houphouët Félix
Rok vydání:	2020
Předmět:	biology Traditional medicine medicine.diagnostic_test Villosa Cholesterol biology.organism_classification medicine.disease Streptozocin chemistry.chemical_compound chemistry Annonaceae Diabetes mellitus visual_art medicine visual_art.visual_art_medium Bark Lipid profile Xylopia
Zdroj:	International Journal of Advanced Biochemistry Research. 4:28-32
ISSN:	2617-4707 2617-4693
DOI:	10.33545/26174693.2020.v4.i2a.53
Popis:	The objective of this study was to assess the anti-lipid-lowering effect of extracts from the bark of Xylopia villosa stems in rats made diabetic by streptozocin. Daonil® 20 mg/kg body weight reduced the total cholesterol concentration in the same way (P ˃ 0.05) as the hydroethanolic extract 200 mg/kg body weight. The triglycerides concentration (1.68 ± 0.10 g/L) of diabetic rats treated with hydroethanolic extract 200 mg/kg body weight became similar (P ˃ 0.05) to that (1.34 ± 0.01 g/L) of non-diabetic control rats. Aqueous extract at a dose of 200 mg/kg body weight normalized (P ˃ 0.05) HDL cholesterol concentration while hydroethanolic extract at a dose of 200 mg/kg body weight, it strictly increased (P
Databáze:	OpenAIRE
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