Indolopyridines with a hetero atom at a position of fusion 8. Reductive C-alkylation of indolo[2,1-a]isoquinolone

Autor:	Svetlana A. Soldatova, J. A. Alarkon, Anatoly T. Soldatenkov, Zh. A. Mamyrbekova, Ryashentseva Margarita A, L. I. Kryvenko, Zh. Ntaganda
Rok vydání:	1994
Předmět:	Fusion Organic Chemistry Heteroatom Alcohol Alkylation Medicinal chemistry chemistry.chemical_compound Electrophilic substitution chemistry Yield (chemistry) Organic chemistry lipids (amino acids peptides and proteins) Isoquinoline Catalytic hydrogenation
Zdroj:	Chemistry of Heterocyclic Compounds. 30:331-334
ISSN:	1573-8353 0009-3122
Popis:	Indolo(2,1-a]isoquinoline was alkylated at C(11) under catalytic hydrogenation conditions over rhenium heptasulfide in a medium of various alcohols. It was shown that the alkylation occurs by an electrophilic substitution mechanism and the yield of the products increases with decreasing acidity of the alcohols.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a7dcde97920b1505c4f07bd9c05d0905 https://doi.org/10.1007/bf01165700 Zobrazit plný text záznamu Full text from SpringerLink