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The formation of the basis for personalized medicine of the future should be based on the prognostic and preventive principles of medicine. The article presents an overview of the information on the method and application of the CME (complex medical expert) analysis. The features of the method, the object domain of its application, its task and methodology are described. The scheme of the options used to increase the efficiency of the method is of interest. The strengths and the shortcomings of the CME analysis noted by experts in the field of its application are given. Results. The authors propose an innovative technology for using the CME model to develop personalized forecasting, preservation, development, and management of health. The advantages of the technology and the urgency of its application are revealed. The new technology is based on the provisions of the development of the theory of the essential adaptation. To ensure the health state, the level of functioning of body systems must be consistent with the optimality, namely with the response norms, which determine the individual phenotype. In the process of the organism adaptation to the conditions of the external environment, the central nervous system and the significant body system (the system with the maximum response norm), which determine the specific and nonspecific responses of the organism, respectively, will be especially active (it is a known fact). Discussion. Dominant systems can actively involve other body systems in the adaptation process by the principle of interaction with them, increasing or decreasing their activity. Taking into account the direction of interaction (inhibition, toning), this fact becomes important for understanding the pathogenesis of diseases, their targeted prevention, and treatment. A comprehensive record of the mechanisms of the formation of a specific and nonspecific reaction is used with the aim of identifying and effectively preventing functional disorders in the body. The CME technology of personalized forecasting, preservation, development and health management eliminates the main drawbacks of CME analysis. On the other hand, the CME analysis technology helps to expand the range of its application, depending on the opportunities and threats of the environment. Conclusion. The presented approach will make it possible to optimally use the human potential to maintain a high quality of life and active longevity. |
