Reversed-Phase High-Performance Liquid Chromatography of Hemin-Based Peptides on a Sorbent Modified with Zinc 4,5-Carboxyphthalocyaninate

Autor: Oleg A. Shpigun, G. D. Brykina, S. M. Matusova, T. V. Zarubina, G. A. Zheltukhina, R. P. Evstigneeva
Rok vydání: 2004
Předmět:
Zdroj: Journal of Analytical Chemistry. 59:266-269
ISSN: 1061-9348
DOI: 10.1023/b:janc.0000018971.44766.46
Popis: The chromatographic retention of some hemin-based peptides on the Diasphere-110-C18 sorbent modified with zinc octa-4,5-carboxyphthalocyaninate was studied. It was demonstrated that this stationary phase is more selective for hemin-peptides than Nucleosil-C18 and Silasorb-600. The conditions of the separation of mixtures of hemin-based peptides were determined, and the parameters of their chromatographic separation were calculated. It was shown that the retention parameters are related to the structure of hemin-based peptides.
Databáze: OpenAIRE