Leptin to Adiponectin ratio as Atherogenic Index in Ischemic Heart Disease Patients

Autor: Anila Jaleel, Humera Afaq, Adnan Zuberi, Muhammad Kashif Nisar, Erum Afaq
Rok vydání: 2019
Předmět:
Zdroj: Journal of Islamabad Medical & Dental College. 7:285-290
ISSN: 2227-3875
Popis: Objective: To determine plasma adiponectin and leptin levels in subjects with and without ischemic heart disease (IHD) and to find the correlation between leptin, adiponectin to the number of coronary vessels disease-using angiography.Patients and Methods: This is a cross-sectional study conducted Ziauddin University. 80 subjects were recruited who were undergoing angiography. Height, weight, Waist and hip circumference were measured. BMI and WHR were calculated accordingly. Venous blood was drawn to measure adiponectin and leptin using ELISA.Results: Leptin to adiponectin ratio (LA ratio) was significantly increased in three and two vessel disease compared with single vessel and non-significant groups.Conclusion: The study shows that adiponectin decreases and leptin increases in multivessel disease. LA ratio has been found to correlate well in two and more than two vessel disease.
Databáze: OpenAIRE