Prevention of Vertical Transmission of HIV in Resource-Limited Countries

Autor: Catherine M. Wilfert, Mary Pat Kieffer, Allison Spensley, Tabitha Sripipatana, Edward Bitarakwate
Rok vydání: 2010
Předmět:
Zdroj: Advances in Experimental Medicine and Biology ISBN: 9781441971845
DOI: 10.1007/978-1-4419-7185-2_4
Popis: Prevention of vertical (i.e., mother-to-child) transmission of HIV is essential to reduce significant HIV-related child morbidity and mortality in developing countries. Globally, pediatric infections comprise about 15% of all new HIV infections each year and virtually all pediatric infections can be prevented by eliminating vertical transmission [1]. The World Health Organization (WHO) recommendations (revised in 2006) for prevention of mother-to-child transmission (PMTCT)1 include a four-pronged comprehensive strategy [2]. Although we acknowledge the critical role that all approaches play in reducing pediatric HIV infection, the focus of this chapter is on strategies that address the third prong: preventing HIV transmission from infected mothers to their infants. Considerable achievements have been made on this front, including many clinical trials demonstrating good efficacy.
Databáze: OpenAIRE