In Vitro and in Vivo Studies of Erythropoiesis during Continuous Ambulatory Peritoneal Dialysis
| Autor: | Andrea Icardi, Silvano Lamperi, Silvia Carozzi |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
medicine.medical_specialty
business.industry Anemia medicine.medical_treatment Continuous ambulatory peritoneal dialysis 030232 urology & nephrology Urology General Medicine 030204 cardiovascular system & hematology medicine.disease In vitro Peritoneal dialysis 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Nephrology In vivo hemic and lymphatic diseases Medicine Chronic renal failure Erythropoiesis Bone marrow business |
| Zdroj: | Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 3:94-96 |
| ISSN: | 1718-4304 0896-8608 |
| DOI: | 10.1177/089686088300300212 |
| Popis: | In order to understand the effect of CAPD on the anemia of chronic renal failure, we studied the behaviour of some hematological parameters and of the colony-formation capacity of bone marrow cells in in vitro cultures in patients undergoing this therapy. Our studies showed a rise in hematocrit, hemoglobin and reticulocyte values, which showed a significant correlation with a recovery of the erythroid cell proliferative activity. Since serum erythropoietin levels do not change, the improvement of bone-marrow function appears to be due to a better clearance (by CAPD) of substances, which inhibit the response of bone marrow to the erythropoietin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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