| Autor: | Eduardo Pandolfi Passos, Carlos B. Souza, Débora Santos, Ana Angélica Gratão, J.S. Cunha Filho, Fernando Monteiro de Freitas |
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| Rok vydání: | 2003 |
| Předmět: |
Azoospermia
Infertility Nephrology endocrine system medicine.medical_specialty medicine.diagnostic_test urogenital system business.industry Urology Testicle medicine.disease Prolactin Andrology Endocrinology medicine.anatomical_structure Internal medicine Biopsy medicine Luteinizing hormone business reproductive and urinary physiology Hormone |
| Zdroj: | International Urology and Nephrology. 35:53-57 |
| ISSN: | 0301-1623 |
| DOI: | 10.1023/a:1025900112600 |
| Popis: | Objective: The objective of the presentstudy was to assess the predictive value ofhormone values, histological analysis for thefinding of motile spermatozoa on testicularbiopsy in nonobstructive azoospermia.Methods: This cross-sectional studyassessed serum follicle-stimulating hormone(FSH), luteinizing hormone, prolactin and totaltestosterone values in 50 patients undergoingtesticular biopsy prior to ICSI. P< 0.05 wasconsidered significant.Results: Recovery was successful in 28cases, and motile spermatozoa were retrieved in7. Significant differences were detectedbetween presence of motile spermatozoa andabsence of spermatozoa in terms of FSH values(P = 0.003, one-way ANOVA). The other variablesdid not present statistical differences. Areceiver operating characteristic curve showedthat FSH levels below 17.00 IU/L werepredictive of motile spermatozoa recovery.Conclusions: FSH values can serve as apredictive factor for the recovery of motilespermatozoa using biopsy in azoospermicpatients. On the other hand, histologicalanalysis and other hormone values were nothelpful in the prediction of motile sperm. |
| Databáze: | OpenAIRE |
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