Tiefe Hirnstimulation bei Multiple-Sklerose-Tremor
| Autor: | Guenther Deuschl, Friederike Sixel-Döring, A. Kupsch, W. Fogel, Reiner Benecke, Christoph Schrader, Lars Timmermann, Jens Volkmann, Rüdiger Hilker, Max Lange |
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| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Ataxia Deep brain stimulation business.industry Thalamotomy Multiple sclerosis medicine.medical_treatment Therapeutic effect General Medicine medicine.disease Trunk Action tremor nervous system diseases Psychiatry and Mental health Physical medicine and rehabilitation Neurology Quality of life medicine Neurology (clinical) medicine.symptom business |
| Zdroj: | Der Nervenarzt. 80:673-677 |
| ISSN: | 1433-0407 0028-2804 |
| DOI: | 10.1007/s00115-009-2697-1 |
| Popis: | Deep brain stimulation (DBS) in the nucleus ventralis intermedius thalami (VIM) is a common procedure to treat disabling tremor in multiple sclerosis which is refractory to pharmacological treatment. The sparse studies on DBS in multiple sclerosis tremor remain controversial regarding the clinical effect on postural and action tremor of hands, trunk and head. Furthermore, it remains unclear whether DBS in multiple sclerosis tremor is superior to thalamotomy and whether patients show an overall improvement in quality of life and activities of daily living. Therefore, the consensus recommendations of the German Deep Brain Stimulation Study Group rely primarily on expert opinion and include (1) extensive preoperative characterisation oftremor, ataxia with accompanying disabilities, status ofthe multiple sclerosis, co-morbidities and burden of disease, (2) careful intraoperative testing of effects and side effects and (3) intensive postoperative testing and programming as well as regular re-evaluation of the therapeutic effect. |
| Databáze: | OpenAIRE |
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