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Introduction:Gonarthrosis is a chronic, degenerative disease that causes pain and stiffness. There are many treatment methods defined as conservative and surgical. Intra-articular hyaluronic acid injection is one of these methods. There are different preparations routinely used in the treatment. There is no clear evidence of which is more effective. We aimed to investigate the effectiveness of HA preparations with different molecular weights on pain and functionality of patients with gonarthrosis. Material and Methods30 of 55 patients (ranging 40-80 years old) diagnosed as bilateral gonarthrosis were enrolled in the study. Patients were randomly divided into 3 groups (Hyalgan (N = 10), Orthovics (N = 10), Synvisc (N = 10)). Patients were evaluated before and after treatment. Clinical examination, Visual Analogue Scale, WOMAC score, stiffness and physical condition, 15 m walking time and 15 steps up and down performance were evaluated. Results There was no significant difference between the groups in terms of age, body mass index (BMI) and symptom duration (p: 0.917, p: 0.721, p: 0.519, respectively). In all three groups, pre-treatment VAS scores (motion, rest and night) significantly decreased after treatment (p 0.05).Conclusion The results of this study revealed no statistically significant difference between HA preparations in WOMAC and VAS scores; However, HA has been found to be effective and should be used in the treatment of early stage gonarthrosis. |
