Stimulation of antibody formation against influenza virus by immunization with the use of ascites tumor

Autor:	A. K. Alekseeva, G. E. Rukavishnikova
Rok vydání:	1975
Předmět:	medicine.diagnostic_test biology General Medicine Immunofluorescence Virology General Biochemistry Genetics and Molecular Biology Virus Microbiology Ovarian tumor Titer Immune system Immunization Antigen medicine biology.protein Antibody
Zdroj:	Bulletin of Experimental Biology and Medicine. 79:178-181
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00808871
Popis:	To obtain immune ascites fluids, rats were immunized three times with living influenza virus and vaccinated with an ascites strain of ovarian tumor (OYa). Considerable stimulation of formation of antiviral antibodies was observed compared with animals not vaccinated with the tumor strain. Immunofluorescence tests revealed an increase in titer of antibodies against both structural antigens of the virus and antigens induced by the virus in the membranes of the infected tumor cells. The phenomenon observed is evidently based on the local accumulation of virus antigens on a considerable scale in cells of the strain OYa.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a77d4588f394e0ff3db7d39f7ab1f575 https://doi.org/10.1007/bf00808871 Zobrazit plný text záznamu Full text from SpringerLink