Central venous catheter infection byAspergillus fumigatus in a patient with B-type non-Hodgkin lymphoma

Autor: Charlotte M. Niemeyer, Yvonne Michalski, Reinhard Berner, Siegfried Sauter
Rok vydání: 1996
Předmět:
Zdroj: Medical and Pediatric Oncology. 27:202-204
ISSN: 1096-911X
0098-1532
DOI: 10.1002/(sici)1096-911x(199609)27:3<202::aid-mpo13>3.0.co;2-h
Popis: Invasive Aspergillus infection is still a major problem in immunocompromised patients. A central venous catheter infection by Aspergillus fumigatus, however, has not yet been reported. We describe the case of a 10-year-old female patient with B-type non-Hodgkin lymphoma treated according to the German chemotherapy protocol NHI-BFM 90. Isolation of Aspergillus fumigatus from the blood was the first hint of invasive aspergillosis. A central venous catheter associated infection was suggested, since Aspergillus was also isolated from the thrombotic tip of the removed catheter. Secondary pulmonary aspergillosis was documented radiologically. The patient was treated successfully by Amphothericin B and Itraconazol and explantation of the central venous catheter under conditions of complete hematopoietic regeneration of the bone marrow with omission of the final chemotherapeutic cycle. © 1996 Wiley-Liss, Inc.
Databáze: OpenAIRE