Novel Use of Impedance Technology Shows That Esophageal Air Events Can Be Temporally Associated With Gastroesophageal Reflux Disease-like Symptoms
| Autor: | Karla Vaz, Kent C. Williams, Frederick W. Woodley, Steven L Ciciora, Sudarshan R. Jadcherla, Carlo Di Lorenzo |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Crying business.industry digestive oral and skin physiology Gastroenterology Reflux Disease medicine.disease digestive system diseases 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine Pediatrics Perinatology and Child Health Etiology GERD medicine 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Journal of Pediatric Gastroenterology & Nutrition. 70:e7-e11 |
| ISSN: | 1536-4801 0277-2116 |
| DOI: | 10.1097/mpg.0000000000002514 |
| Popis: | A few studies have shown that esophageal air events (EAEs), such as air-swallows, may be associated with symptoms that have historically been associated with gastroesophageal reflux disease (GERD). To objectively test a hypothesis that all EAE types (air-swallows, supragastric belches and gastric belches) can be associated with GERD-like symptoms, we removed the impedance "tags" from the GER episodes (placed during autoscan) and instead tagged either air-swallows, supragastric belches or gastric belches in each of 3 copies of the 24-hour impedance tracing for 2 infant patients who presented with symptoms suggestive of GER as an etiology. Impedance system software (MMS) analyses revealed that, in both infants, all EAE types were significantly associated (SAP >95%) with 1 or more of the GERD-like symptom types (cough, pain/crying, back-arching, and gagging). These data underscore the importance of considering other diagnoses when developing management strategies for treating GERD-like symptoms in infants. |
| Databáze: | OpenAIRE |
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