Selenium and its compounds – Determination of selenite and selenate in urine by anion-exchange chromatography-ICP-MS

Autor: Jäger, Thomas, Göen, Thomas, Michalke, Bernhard, Hartwig, Andrea, MAK Commission
Jazyk: angličtina
Rok vydání: 2022
Předmět:
human biomonitoring
high-performance liquid chromatography with inductively coupled plasma-mass spectrometry
environmental exposure
Arbeitsplatz
Umweltbelastung
Analyses in Biological Materials
general population
HBM
Urin
Hintergrundbelastung
intoxication
biomonitoring method
Selen
ICP-MS
HPLC-ICP-MS
background exposure
selenium
biologisches Monitoring
Biomonitoringmethode
employee
Methode
speciation analysis
Hochleistungs-Flüssigkeitschromatographie mit induktiv gekoppelter Plasma-Massenspektrometrie
analytical method
Arbeiter
Vergiftung
Analysen in biologischem Material
urine
Humanbiomonitoring
Arbeitsplatzbelastung
poisoning
workplace
biological monitoring
Arbeitnehmer
Analysenmethode
Intoxikation
selenium species
biomonitoring
method
Speziesanalytik
HPLC
Selenspezies
workplace exposure
worker
Allgemeinbevölkerung
DOI: 10.34865/bi778249ae7_2or
Popis: The working group “Analyses in Biological Materials” of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area developed and verified the presented biomonitoring meth-od. This analytical method is used to determine selenite and selenate in urine, which are separated by anion-exchange chromatography and subsequently detected by inductively coupled plasma-mass spectrometry (ICP MS). Calibration is performed using standard solutions, which are prepared in pooled urine, processed, and analysed analogously to the samples. The analytical method allows for the sensitive and precise determination of selenite and selenate without in-terferences by other selenium species. The low limits of quantitation enable the determination of very low urinary con-centrations of selenite or selenate. However, selenite and selenate do not normally contribute substantially to total sele-nium content in urine.
Databáze: OpenAIRE
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