| Popis: |
The crystalline lens of the eye has long been a model system for the complexities of tissue induction and morphogenesis as well as cell specification and differentiation. The unique protein content of the lens has also been the subject of intensive study in respect to stability, aggregation and longevity in the absence of vasculature and innervations. Cataract, the main pathology of the lens, occurs as a result of direct alterations to protein folding, stability or solubility, or indirectly via altered cellular physiology. |
