Vitamin B12 Deficiency in Relation to Metformin Use in Adults with Type-2 Diabetes Mellitus

Autor: Najmush Shakireen, Saqib Qayyum, Abdul Rehman Arshad, Muhammad Amir, Fuad Ahmad Siddiqi, Anum Gul
Rok vydání: 2023
Předmět:
Zdroj: Life and Science. 4:4
ISSN: 2708-2970
2521-0475
DOI: 10.37185/lns.1.1.271
Popis: Objective: To find the correlation between serum vitamin B12 levels in metformin users among type-2 diabetics.Study Design: Cross-sectional Study.Place and Duration of Study: The study was carried out at the Department of Medicine of Combined Military Hospital, Peshawar, Pakistan from April 2021 to September 2021.Materials and Methods: Using a consecutive sampling technique, patients were selected from both outdoor and indoor medical health facility Blood tests were performed on all patients and serum vitamin B12 level was assessed, a level less than 200 pg/ml was considered deficient. The comparison was made among patients taking metformin and those not on metformin.Results: 148 patients were enrolled, consisting of an equal proportion of cases and controls i.e. 74 patients in each group, with a mean age of 44.09± 10.61 and 46.15± 10.64 respectively. Vitamin B12 deficiency was found more in metformin user group 34 (45.94%) than in patients not on metformin 11 (14.86%) (p
Databáze: OpenAIRE