Chiral thiophosphoramide catalyzed asymmetric aryl transfer reactions for the synthesis of functional diarylmethanols

Autor:	Huayin Huang, Hua Zong, Yabai Wang, Ling Song
Rok vydání:	2017
Předmět:	010405 organic chemistry Chemistry Aryl Organic Chemistry Chiral ligand 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound Organic chemistry Physical and Theoretical Chemistry Thiophosphoramide
Zdroj:	Tetrahedron: Asymmetry. 28:90-97
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2016.11.011
Popis:	In this investigation, chiral thiophosphoramide 3d was easily prepared from chiral (1R,2R)-1,2-diphenylethylenediamine and then applied as an efficient chiral ligand in the catalytic asymmetric arylation reactions of various aromatic aldehydes. The corresponding diarylmethanol products were produced with good to excellent yields (up to 98%) and enantioselectivities (up to 94%). The recovery of chiral ligand 3d could be as high as 96%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a73af1055c6d766acd19ab5ecb2db57a https://doi.org/10.1016/j.tetasy.2016.11.011 Zobrazit plný text záznamu Full Text from ScienceDirect