Acetonitrile-Induced Destabilization in Liposomes
| Autor: | Izumi Nishio, Kazunari Yoshida, Keitaro Horii, Akito Takashima, Ryohei Mitsumori |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Liposome
Aqueous solution Artificial cell Chemistry Vesicle Thermal fluctuations 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Colloid and Surface Chemistry Membrane Chemistry (miscellaneous) Biophysics Molecule 0210 nano-technology Acetonitrile |
| Zdroj: | Colloids and Interfaces. 2:6 |
| ISSN: | 2504-5377 |
| DOI: | 10.3390/colloids2010006 |
| Popis: | To understand the behavior of cellular interfaces, it is important to clarify the effect of chemical compounds on artificial cell membranes. In this study, an aqueous acetonitrile solution was mixed with a suspension of lipid vesicles, and the changes in vesicle behavior arising as a result of acetonitrile application were observed. The fast Fourier transformations (FFTs) of the membrane waviness/crinkliness of the vesicles were carried out, and the membrane thermal fluctuations were analyzed. The experimental results show that the addition of acetonitrile molecules enhances the fluctuation of lipid membranes. In particular, the k = 2 mode fluctuation was significantly enhanced. This finding is expected to lead us to a further understanding of the fundamental properties of living cells. |
| Databáze: | OpenAIRE |
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