Perforated Goblet Cell Carcinoid Tumors of the Appendix: Navigating the Management Conundrum
| Autor: | Suman B. Koganti, Brian F. Gilchrist, Tresara C. Bell |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
biology business.industry General surgery Chromogranin A Perforated appendix medicine.disease Appendix 030218 nuclear medicine & medical imaging Natural history 03 medical and health sciences Management strategy 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis biology.protein Surveillance Epidemiology and End Results Medicine Surgery Hyperthermic intraperitoneal chemotherapy business Goblet cell carcinoid |
| Zdroj: | International Surgery. 102:131-136 |
| ISSN: | 2520-2456 0020-8868 |
| Popis: | Appendix is the most common site of occurrence for a goblet cell carcinoid tumor. A diagnosis of an appendiceal goblet cell carcinoid is made in retrospect the majority of the time. These tumors are best treated with a right hemicolectomy and adjuvant therapies tailored according to the presence or absence of residual disease. Presentation as a perforated appendix is seen in 16% of these tumors. The natural history and the ideal management strategy in such a scenario are not well described. In those with peritoneal spread cytoreductive surgery with HIPEC (hyperthermic intraperitoneal chemotherapy) offers the best disease-free and progression-free survival. Close follow-up with cross-sectional imaging helps in identifying recurrences at the earliest. Multimodality management involving patient participation in every aspect of care accomplishes high-value care in the treatment of these tumors. |
| Databáze: | OpenAIRE |
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