Tardive dyskinesia and coupling constraints in inter-limb tremor

Autor: Robert L. Sprague, Karl M. Newell
Rok vydání: 1996
Předmět:
Zdroj: Human Movement Science. 15:237-251
ISSN: 0167-9457
DOI: 10.1016/0167-9457(95)00045-3
Popis: The coupling of inter-limb tremor in finger and arm postural tasks was examined in adult tardive dyskinetic, severely/profoundly mentally retarded, tardive dyskinetic and severely/profoundly mentally retarded, and normal healthy subjects. In finger tremor, the index fingers were found to operate independently in the time and frequency domains for normal adults but there was a modest level of coupling in the time domain in both tardive dyskinetic groups. Inter-limb coupling in the time and frequency domains was enhanced in arm tremor for all groups, with the effect stronger in the time domain for the tardive dyskinetic groups and in the frequency domain for the groups of normal intelligence. There was also a persistent phase lag in the coupling of the two limbs in both postural tasks for the tardive dyskinetic subjects. These data show that prolonged intake of neuroleptic medication constrains inter-limb coupling even when the task demands do not explicitly require such a coordination strategy. The coupling effects are stronger in arm tremor which suggests that the mass of the effector system is also a factor in constraining the coupling of inter-limb coordination.
Databáze: OpenAIRE