Phase I trial of nelfinavir added to cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancer
Autor: | Rosa P. Castillo, J.M. Pearson, Joseph A. Lucci, Lilie L. Lin, Arlene E. Garcia-Soto, Fiona Simpkins, Jennifer J. Hu, Nathalie Dauphin McKenzie, Lorraine Portelance |
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Rok vydání: | 2015 |
Předmět: |
Oncology
Cervical cancer Cisplatin Cancer Research medicine.medical_specialty Chemotherapy Network Functions Virtualization business.industry medicine.medical_treatment Locally advanced medicine.disease Surgery Nelfinavir Internal medicine Medicine Protease inhibitor (pharmacology) business Pelvic radiotherapy medicine.drug |
Zdroj: | Journal of Clinical Oncology. 33:TPS5619-TPS5619 |
ISSN: | 1527-7755 0732-183X |
DOI: | 10.1200/jco.2015.33.15_suppl.tps5619 |
Popis: | TPS5619 Background: Despite platinum based chemoradiation (C-XRT), 40-50% of women with locally advanced cervical cancer will die from their disease. Nelfinavir (NFV), a protease inhibitor, has bee... |
Databáze: | OpenAIRE |
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