Does Elevated Plasma Triglyceride Level Independently Predict Impaired Fasting Glucose?
| Autor: | Pamela J. Schreiner, Zhezhen Jin, Susan X. Lin, Alain G. Bertoni, Richard Younge, Moyses Szklo, Ivan Berlin, Christopher T. Sibley |
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| Rok vydání: | 2013 |
| Předmět: |
Advanced and Specialized Nursing
Research design medicine.medical_specialty Diabetes risk business.industry Endocrinology Diabetes and Metabolism Incidence (epidemiology) Hazard ratio Ethnic group nutritional and metabolic diseases 030209 endocrinology & metabolism 030204 cardiovascular system & hematology medicine.disease Impaired fasting glucose 3. Good health 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes mellitus Internal medicine Internal Medicine medicine business Chinese americans |
| Zdroj: | Diabetes Care. 36:342-347 |
| ISSN: | 1935-5548 0149-5992 |
| DOI: | 10.2337/dc12-0355 |
| Popis: | OBJECTIVE Elevated plasma triglycerides (TGs) have been included in diabetes risk prediction models. This study examined whether elevated TGs predict risk for impaired fasting glucose (IFG). RESEARCH DESIGN AND METHODS This study used the baseline and longitudinal follow-up data from the Multi-Ethnic Study of Atherosclerosis (MESA). The analysis included non-Hispanic whites, African Americans, Hispanics, and Chinese Americans 45–84 years of age who had fasting glucose RESULTS The incidence rate of developing IFG was 59.1 per 1,000 person-years during the median 4.75 years of follow-up. African Americans and Hispanics had a higher incidence rate of IFG compared with non-Hispanic whites among people with normal TG concentrations. Elevated TGs (>150 mg/dL) at baseline were independently associated with the incidence of IFG with an adjusted hazard ratio of 1.19 (95% CI 1.04–1.37). However, its predictive value for identifying people at risk for IFG was poor, with CONCLUSIONS Elevated TGs were moderately associated with risk for IFG, and it was a poor risk prediction tool for IFG. |
| Databáze: | OpenAIRE |
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