Extraction of betulin from birch bark and study of its physico-chemical and pharmacological properties

Autor:	Evgeniya S. Skurydina, O. F. Veselova, Iu. N. Maliar, Svetlana A. Kuznetsova, Galina P. Skvortsova
Rok vydání:	2014
Předmět:	Potassium hydroxide Betulin Chemistry Sodium Organic Chemistry Extraction (chemistry) chemistry.chemical_element Nuclear magnetic resonance spectroscopy Biochemistry chemistry.chemical_compound Sodium hydroxide Elemental analysis visual_art visual_art.visual_art_medium Organic chemistry Bark
Zdroj:	Russian Journal of Bioorganic Chemistry. 40:742-747
ISSN:	1608-330X 1068-1620
DOI:	10.1134/s1068162014070073
Popis:	Betulin-containing products were obtained in a yield of about 40% from absolutely dry birch bark. The content of betulin in the products was 74–75% or 85–89% depending on the presence of sodium or potassium hydroxide, respectively. The one-step method of extraction of high-purity betulin (97.7%) is presented. Betulin was identified by physic-chemical methods, i.e., elemental analysis, IR and NMR spectroscopy, and electron scanning microscopy. The thermal characteristics of betulin were also studied. It was shown that betulin exhibits gastroprotective, hepatoprotective, and capillary-strengthening properties.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6d234c11ebc8b90507ffa1aef9ad3dc https://doi.org/10.1134/s1068162014070073 Zobrazit plný text záznamu Full text from SpringerLink