Complementary fluorescence and optoacoustic imaging for monitoring of photodynamic therapy of glioma employing BPD based nanoconstructs: pilot animal studies

Autor:	Elena B. Kiseleva, Anastasiya S. Nerush, Tayyaba Hasan, Valeriya Perekatova, Shazia Bano, V. I. Plekhanov, Srivalleesha Mallidi, Ekaterina A. Sergeeva, Mikhail Yu. Kirillin, Anna Orlova, Marina V. Shirmanova, E. Sergeev, Diana V. Yuzhakova, D. A. Kurakina, Ilya V. Turchin, Pavel Subochev
Rok vydání:	2020
Předmět:	Fluorescence-lifetime imaging microscopy Liposome biology Chemistry medicine.medical_treatment Photodynamic therapy 02 engineering and technology 021001 nanoscience & nanotechnology biology.organism_classification medicine.disease Photobleaching Fluorescence Nude mouse In vivo Glioma 0202 electrical engineering electronic engineering information engineering Biophysics medicine 020201 artificial intelligence & image processing 0210 nano-technology
Zdroj:	2020 International Conference Laser Optics (ICLO).
Popis:	We report on a novel approach to monitor photodynamic therapy procedure based on the simultaneous fluorescence and optoacoustic imaging with the use of a liposome nanoconstructs contain benzoporphyrin derivatives and the fluorescent IRDye800 dye. We demonstrate the results of a preliminary in vivo study with combined fluorescence and optoacoustic custom-made setups on a NUDE mouse with human glioblastoma U-87.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6c63756d513bf3c38195bbf838b9543 https://doi.org/10.1109/iclo48556.2020.9285541 Zobrazit plný text záznamu