| Autor: |
Yu Wang, Ya Li Wei, Jian Nan Wang, Dan Sun |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Advanced Materials Research. 796:136-139 |
| ISSN: |
1662-8985 |
| DOI: |
10.4028/www.scientific.net/amr.796.136 |
| Popis: |
Silk fibroin (SF) has good biocompatibility and has been used to construct small caliber artificial blood vessels. As a vascular graft, the antithrombogenicity is the first important performance. The aim of this study was to evaluate the anticoagulant property of polyethylene glycol diglycidyl ether (PEG-DE) crosslinked and ethanol treated SF materials by investigating the platelet adhesion. Dacron and PTFE were parallel studied as the controls. Results showed that: the platelet adhesion ratios on the ethanol treated SF films were significantly lower than that on the Dacron and PTFE; the platelet adhesion ratios on the PEG-DE crosslinked SF films were higher than that on the ethanol treated SF films and slightly increased with increasing the proportion of the PEG-DE. But the platelet adhesion ratios on all of the PEG-DE crosslinked SF films were significantly lower than that on the controls. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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