| Autor: |
Szymon Piatek, Grzegorz Panek, Zbigniew Lewandowski, Dominika Piatek, Przemyslaw Kosinski, Mariusz Bidzinski |
| Rok vydání: |
2021 |
| Popis: |
Objective of this study was to evaluate nadir CA-125 in patients with epithelial ovarian cancer. 168 patients, who achieved complete remission (no clinical and radiological signs, CA-125< 35 U/ml) after first line treatment were enrolled in the study. The relation between CA-125 and survival were examined using generalized additive models applied to the Cox proportional hazards model. The median CA-125 concentration after the treatment was 10 U/ml (2.7-35 U/ml). No correlation between CA-125 nadir and overall survival was found (p linear = 0.13; p nonlinear = 0.52). Patients with CA-125 serum concentrations of 11 - 25 U/ml and 26 - 35 U/ml had significantly higher risk of recurrence compared to patients with CA-125 concentration ≤ 10 U/ml with HR = 1.865 (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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