Smoking-Related Diseases
| Autor: | Helmut Popper, Bruno Murer |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Lung business.industry Interstitial lung disease respiratory system medicine.disease Desquamative interstitial pneumonia Pulmonary hypertension respiratory tract diseases Lymphatic system medicine.anatomical_structure Fibrosis Bronchiolitis Medicine Respiratory system business |
| Zdroj: | Essentials of Diagnostic Pathology ISBN: 9783030226626 |
| DOI: | 10.1007/978-3-030-22664-0_22 |
| Popis: | Smokers demonstrate a wide range of clinicopathologic entities in the lung that include Respiratory Bronchiolitis combined Interstitial Lung Disease (RB-ILD), Desquamative Interstitial Pneumonia (DIP), and Pulmonary Langerhans Cell Histiocytosis (PLCH). Although they have been considered separate lesions in various classifications of interstitial lung diseases, these entities share pathogenesis and a number of clinical, radiologic, and pathologic features, suggesting they represent a spectrum of patterns of interstitial lung diseases occurring in smokers and, in an individual case, we can encounter hybrids of RB-ILD, DIP, and PLCH. Small airway injury including submucosal and adventitial fibrosis, increased bronchus-associated lymphoid tissue, and pulmonary hypertension are also associated with smoking. It has only recently been observed that fibrosis of alveolar wall occurs in smokers (clinically occult smoking-related interstitial fibrosis). |
| Databáze: | OpenAIRE |
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