Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted xanthine derivatives
Autor: | Manisha Sathe, Prabal Bandyopadhyay, Pratibha Sharma, M. P. Kaushik |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 53:4631-4635 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2012.04.135 |
Popis: | Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed to be more efficient than IIDQ and polymer-supported carbodiimide (PS-EDC). |
Databáze: | OpenAIRE |
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