Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted xanthine derivatives

Autor: Manisha Sathe, Prabal Bandyopadhyay, Pratibha Sharma, M. P. Kaushik
Rok vydání: 2012
Předmět:
Zdroj: Tetrahedron Letters. 53:4631-4635
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2012.04.135
Popis: Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed to be more efficient than IIDQ and polymer-supported carbodiimide (PS-EDC).
Databáze: OpenAIRE