Studies on Biological Evaluation of Cyanopyrans and Pyrazolines Using Microwave Assisted Synthesis

Autor:	K. R. Ramchandran, T. V. Radhakrishnan, Hansa Parekh, H. M. Kanjariya
Rok vydání:	2004
Předmět:	chemistry.chemical_compound chemistry Hydrazine Microwave irradiation Organic chemistry General Medicine Antimicrobial Hydrate Microwave assisted Nuclear chemistry Biological evaluation Malononitrile
Zdroj:	ChemInform. 35
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200444144
Popis:	A series of 3-cyanopyrans 3a-k and pyrazolines 4a-k have been synthesied by condensing 4'-(a-isopropyl-p-chlorophenyl-acetamidophenyl)-3-aryl-2-propen-1-ones 2 with malononitrile and hydrazine hydrate respectively. Moreover, a simple and efficient method has been deviced for the rapid and improved synthesis of pyrazolines using microwave irradiation (MWI). All the products have been characterised by elemental analyses, IR, 'H NMR, mass spectral study and screened for their antimicrobial activity against several microbes and antitubercular activity against Mycobacterium tuberculosis H 3 7 Rv.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6569576f5e05e0a9dcbbb22636d6286 https://doi.org/10.1002/chin.200444144 Zobrazit plný text záznamu Plný text