An update on diagnosis and therapeutics for type-2 diabetes mellitus

Autor: Shyamaladevi Babu
Rok vydání: 2023
Předmět:
Zdroj: Bioinformation. 19:295-298
ISSN: 0973-2063
0973-8894
Popis: Type-2 Diabetes mellitus is a common metabolic disorder and is combined with co-morbidities, such as obesity, hyperlipidemia, hypertension and cardiovascular disease which taken together, comprise the ‘Metabolic Syndrome’. This disease causes crucial morbidity and mortality at considerable expense to patients, their families and society. Different categories of drugs such as insulin secretagogues, insulin sensitizers, alpha-glucosidase inhibitors, GLP-1 agonists, DPP4 inhibitors, Dual PPAR agonists etc are used for its management. In this review, we have highlighted the recent advances in diagnosis and therapeutics used in the treatment of type-2 diabetes mellitus. The classical and online-literature were studied in order to compile the data which includes the electronic search engine such as Scopus, Google Scholar, Sci Finder, PubMed and Web of Science etc. The scientific data showed that at present, there are different families of oral and injectable drugs are at hand for the treatment of T2DM which has deleterious side effects. Hence, we need to develop a novel, safety and effective agents that will improve the quality of life of T2DM patients, considering the properties of the treatment such as effectiveness and durability of lowering blood Glucose, risk of hypoglycemia and diabetes complications.
Databáze: OpenAIRE