The Role of Humoral and Cellular Factors in the Stimulation of Nonspecific Resistance Induced by Endotoxin

Autor: Zs. Pusztai-Markos
Rok vydání: 1975
Předmět:
Zdroj: Gram-Negative Bacterial Infections and Mode of Endotoxin Actions ISBN: 9783709183984
DOI: 10.1007/978-3-7091-8396-0_20
Popis: The ability of bacterial endotoxins (ET) to alter the course of experimental infections is well-known. The transient increase in homologous and heterologous resistance that develops within hours after ET administration may be related to enhanced macrophage and reticuloendothelial activity (1, 2) and/or to enhancement of preexisting specific antibody titres according to published observations (3, 4). Furthermore, it has been suggested that at least a part of the biological activities provoked by ET are based on a hypersensitivity state of the host (5, 6).
Databáze: OpenAIRE