Comparison of Solid and Solvent - Based Syntheses, Characterization and Antioxidant Property of Metal Complexes of Sodium Diclofenac

Autor:	Bale At, W. A. Osunniran, Joshua A. Obaleye, Yusuf Oloruntoyin Ayipo, M. A. Adeyemo
Rok vydání:	2020
Předmět:	Metal Antioxidant Chemistry Solvent based visual_art medicine.medical_treatment visual_art.visual_art_medium medicine Diclofenac Sodium Nuclear chemistry Characterization (materials science)
Zdroj:	Fountain Journal of Natural and Applied Sciences. 9
ISSN:	2354-337X 2350-1863
DOI:	10.53704/fujnas.v9i1.291
Popis:	Mechanosynthesis and solvent – based syntheses of transition metals (Ni, Co and Zn) complexes of Sodium diclofenac has been carried out by 1:1 molar ratio of the ligand to metal salts respectively. The synthesis of the metal complexes were confirmed by melting point determination, FT-IR (Fourier Transform Infra-red) and UV-visible spectroscopies. The ligand showed bidentate coordination to the metal ions through carboxylate moiety. Octahedral geometry was proposed for all the metal complexes. The antioxidant property of metal complexes was determined using DPPH (1,1-diphenyl-2-picrylhydrazyl) assay with Ascorbic acid as control. The antioxidant evaluation results revealed that the synthesized metal complexes are promising antioxidant agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6404fecfe0f4b24761935b1afc8c7ec https://doi.org/10.53704/fujnas.v9i1.291 Zobrazit plný text záznamu