Kidney Volume in Kidney Function Assessment: Determinants and Clinical Correlates in Systemic Hypertension and Chronic Kidney Disease in Southwestern, Nigeria
| Autor: | AdebolaYusuf Ao, Nwogbe Ci, Ajiboye Of, Uduagbamen Pk, Oludiran Ta, Thompson Mu |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Kidney Creatinine urogenital system business.industry Urology Renal function Kidney Volume Albumin/creatinine ratio urologic and male genital diseases medicine.disease female genital diseases and pregnancy complications chemistry.chemical_compound Blood pressure medicine.anatomical_structure chemistry Medicine Hemoglobin business Kidney disease |
| Zdroj: | Open Journal of Nephrology. 10:298-310 |
| ISSN: | 2164-2869 2164-2842 |
| Popis: | Background: The kidney volume is a very reliable ultrasound measure, reflecting contributions from all kidney parts. It could be affected by gender, body size and disease conditions. Its use in renal function assessment is based on its correlation with the glomerular filtration rate (GFR). Objectives: To assess the determinants and clinical correlates of kidney volume in hypertension and in chronic kidney disease (CKD). Materials and Methods: The two-center study was carried out at the Federal Medical Centre, Abeokuta (June-December 2017) and Babcock University Teaching Hospital, Ilishan-Remo (August 2019-January 2020). The kidneys of sixty participants who had hypertension without kidney disease (HWKD) and 58 with CKD were scanned from the front and back and their blood samples were taken for electrolytes and hemoglobin concentration. Result: The participants with CKD were significantly older than those with hypertension, P < 0.001. The mean kidney volume of hypertensives, 132.4 ± 18.3, was significantly higher than those with CKD, 63.7 ± 5.9, P < 0.001. The glomerular filtration rate (GFR) and hemoglobin concentration were significantly higher in hypertensives than in CKD, P < 0.001, P < 0.001 respectively. The systolic blood pressure (SBP), creatinine and the albumin creatinine ratio (ACR) were significantly higher in CKD than in hypertension, P < 0.001, P < 0.001 and P < 0.001 respectively. Conclusion: The mean kidney volume was higher in hypertension and in males. The GFR and hemoglobin levels were significantly higher in hypertension than in CKD while blood pressure and ACR were significantly higher in CKD than in hypertension. Kidney volume was positively and negatively correlated with GFR and ACR respectively. |
| Databáze: | OpenAIRE |
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