Efficacy of estazolam

Autor: Mark W. Pierce, Vincent S. Shu
Rok vydání: 1990
Předmět:
Zdroj: The American Journal of Medicine. 88:S6-S11
ISSN: 0002-9343
DOI: 10.1016/0002-9343(90)90279-m
Popis: The hypnotic efficacy of estazolam, a triazolobenzodiazepine, has been established in well-controlled sleep laboratory and outpatient clinical trials. Estazolam 1.0 mg and 2.0 mg significantly improves sleep latency, total sleep time, number of nocturnal awakenings, depth of sleep, and sleep quality in adults with chronic insomnia. Long-term studies indicate that estazolam 2.0 mg remains an effective hypnotic for at least six weeks of continuous nightly administration with no evidence of clinically significant tolerance. Estazolam is an effective treatment for situational insomnia and significantly improves sleep in patients with insomnia associated with moderately severe anxiety or depression.
Databáze: OpenAIRE