Highly efficient utilization of H2O2 for oxygenation of organic sulfides catalyzed by [γ-SiW10O34(H2O)2]4−

Autor:	Mark A. Kinch, Tuan D. Phan, Julia E. Barker, Tong Ren
Rok vydání:	2005
Předmět:	chemistry.chemical_classification Molar concentration Sulfide Organic Chemistry Sulfoxide Phosphate Biochemistry Medicinal chemistry Catalysis Sulfone chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Imidazole Hydrogen peroxide
Zdroj:	Tetrahedron Letters. 46:397-400
ISSN:	0040-4039
Popis:	Remarkable efficiency of hydrogen peroxide utilization is reported for oxygenation of four organic sulfides catalyzed by a divacant lacunary silicotungstate, (Bu 4 N) 4 [γ-SiW 10 O 34 (H 2 O) 2 ] ( 1 ), under mild conditions. The addition of imidazole, phosphate, or carboxylates significantly enhances the rate of organic sulfide oxygenation. Most notably, use of 1 and imidazole, both at 1% molar concentration, resulted in the quantitative conversion of phenylsulfide to sulfoxide with 1 equiv of H 2 O 2 in 3 h, and to sulfone with 2 equiv of H 2 O 2 in 6 h.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a610e990cddb86cf8bd172ed5796f88a https://doi.org/10.1016/j.tetlet.2004.11.107 Zobrazit plný text záznamu Full Text from ScienceDirect