Facile One-Pot Conversion of Aldehydes into Amides

Autor:	Robert C. Mebane, Samuel T. Chill
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Cascade reaction chemistry Nitrile Tandem Amide Organic Chemistry Organic chemistry Hydroxylamine Hydrochloride Hydrogen peroxide Aldehyde
Zdroj:	Synthetic Communications. 40:2014-2017
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397910903219443
Popis:	A facile one-pot synthesis of amides from aldehydes has been developed. This tandem process involves the formation of a nitrile intermediate obtained from the reaction of an aldehyde with hydroxylamine hydrochloride in dimethylsulfoxide at 100°C and the subsequent treatment of the nitrile with basic hydrogen peroxide. The resulting amide products were produced in good yields (67–95%) and purity (>95%).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6101accb97c1fde5e2bf5ab071bf235 https://doi.org/10.1080/00397910903219443 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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