Group A streptococcal toxic shock like syndrome induced by contusion

Autor: Rie Kajita, Hitoshi Ieshima, Kenji Ooe, Nobuhiro Okano, Kazunori Kasama, Yoshikata Shimizu
Rok vydání: 1994
Předmět:
Zdroj: Nihon Kyukyu Igakukai Zasshi. 5:285-289
ISSN: 1883-3772
0915-924X
DOI: 10.3893/jjaam.5.285
Popis: A 37-year-old, previously healthy man, with no history of serious infection, sustained a contusion on the flexor side of his right thigh. Severe pain and swelling at the wound area were present the following day. He had fever, hypotension, anuria, stupor and right leg ischemia, and was admitted on the 3rd post-injury day. Although incisions were twice made in the swollen portion of his thigh for decompression, shortly after admission, the skin around the incision became necrotic on the 4th day. At the same time, adult respiratory distress syndrome, disseminated intravascular coagulation, and profound hypotension developed rapidly, and cathecolamine infusion, mechanical ventrilation, hemodialysis and debridement of the necrotizing skin and muscle were needed. However, erythema with blisters extended to both legs, the lower abdomen and bilateral chest, and he died due to circulatory collapse on the 6th day. Group A streptococcal organisms were isolated from the necrotizing skin, muscles and blood. The serotype of this strain was M22, which produces exotoxins type B and C in vitro.
Databáze: OpenAIRE