Guided optimization of a crystallization-induced diastereomer transformation to access a key navoximod intermediate
Autor: | Andrew J. Kukor, Frédéric St-Jean, Andreas Stumpf, Thomas C. Malig, Katarzyna A. Piechowicz, Kenji Kurita, Jason E. Hein |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Reaction Chemistry & Engineering. |
ISSN: | 2058-9883 |
DOI: | 10.1039/d3re00077j |
Popis: | The crystallization-induced diastereomer transformation of a precursor to navoximod was investigated using online HPLC and optimized with inline racemization. |
Databáze: | OpenAIRE |
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